Am I becoming antisocial or was I born this way?

When I was little I only talked to certain people ( my mom, dad, sisters, and 3 friends) not even my aunts uncles and cousins. When I got older (in the fifth grade) people started being mean and using me because I wouldn't really talk to anyone (I was considered a "smart kid") In middle school I made friends with I guess you can call the "popular kids" or what ever and they all really liked me and I had a lot of friends. Now I'm in high school and I really don't like talking to anyone and I lost the trust in most of the people I was friends with before. Everyone seems to dislike me because of it. I'm under a lot of stress to change my life but its like I never improve. I've gotten very depressed. I'm less stress when I'm not trying to be around people. Should I just be antisocial and remain somewhat comfortable or should I try to be friends with people and possibly have another brake down